10 Largest pharmacies in the United States in 2025
What is the largest pharmacy in the United States?
Express Scripts is the largest pharmacy the United States in 2025.What are the largest pharmacies in the United States in 2025?
Express Scripts, CVS Pharmacy and Walgreens are the largest pharmacies in the United States in 2025 based on the number of locations. Express Scripts has the most number of locations with 45,948 locations across 52 states and territories. CVS Pharmacy has 9,027 and Walgreens has 8,138 locations in the US. These three together make 86.82% of the largest 10 pharmacies in the US.
| Rank | Brand | Number of Locations | States Present In | Cities Present In | Download Dataset | |
|---|---|---|---|---|---|---|
| #1 |
|
Express Scripts | 45,948 | 52 | 6,544 | |
| #2 |
|
CVS Pharmacy | 9,027 | 51 | 3,442 | |
| #3 |
|
Walgreens | 8,138 | 53 | 3,344 | |
| #4 |
|
Health Mart | 4,331 | 52 | 2,258 | |
| #5 |
|
Good Neighbor Pharmacy | 2,352 | 53 | 1,584 | |
| #6 |
|
Genoa Healthcare | 766 | 48 | 555 | |
| #7 |
|
Rite Aid | 764 | 15 | 558 | |
| #8 |
|
Safeway Pharmacy | 753 | 18 | 456 | |
| #9 |
|
Albertsons Pharmacy | 306 | 15 | 187 | |
| #10 |
|
The Medicine Shoppe Pharmacy | 305 | 41 | 272 |
Disclaimer: Brand logos are used for visual representation only and do not imply endorsement or affiliation.
Learn more about 10 Largest pharmacies in the United States in 2025
Express Scripts
There are 45,948 Express Scripts pharmacies in the United States as of August 17, 2023. The state and territory with the most number of Express Scripts locations in the US is California, with 4,879 pharmacies, which is about 11% of all Express Scripts pharmacies in the US.
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CVS Pharmacy
There are 9,027 CVS Pharmacy locations in the United States as of July 07, 2025. The state and territory with the most number of CVS Pharmacy locations in the US is California, with 1,063 locations, which is about 12% of all CVS Pharmacy locations in the US.
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Walgreens
There are 8,115 Walgreens pharmacies in the United States as of August 11, 2025. The state and territory with the most number of Walgreens locations in the US is Florida, with 788 pharmacies, which is about 10% of all Walgreens pharmacies in the US.
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Health Mart
There are 4,331 Health Mart pharmacies in the United States as of June 24, 2025. The state and territory with the most number of Health Mart locations in the US is California, with 504 pharmacies, which is about 12% of all Health Mart pharmacies in the US.
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Good Neighbor Pharmacy
There are 2,352 Good Neighbor Pharmacy locations in the United States as of June 25, 2025. The state and territory with the most number of Good Neighbor Pharmacy locations in the US is California, with 255 locations, which is about 11% of all Good Neighbor Pharmacy locations in the US.
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Genoa Healthcare
There are 766 Genoa Healthcare locations in the United States as of July 26, 2024. The state and territory with the most number of Genoa Healthcare locations in the US is Arizona, with 66 locations, which is about 9% of all Genoa Healthcare locations in the US.
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Rite Aid
There are 764 Rite Aid pharmacies in the United States as of July 15, 2025. The state and territory with the most number of Rite Aid locations in the US is California, with 256 pharmacies, which is about 34% of all Rite Aid pharmacies in the US.
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Safeway Pharmacy
There are 753 Safeway Pharmacy locations in the United States as of July 02, 2025. The state and territory with the most number of Safeway Pharmacy locations in the US is Washington, with 165 locations, which is about 22% of all Safeway Pharmacy locations in the US.
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Albertsons Pharmacy
There are 306 Albertsons Pharmacy locations in the United States as of July 02, 2025. The state and territory with the most number of Albertsons Pharmacy locations in the US is California, with 87 locations, which is about 28% of all Albertsons Pharmacy locations in the US.
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The Medicine Shoppe Pharmacy
There are 305 The Medicine Shoppe Pharmacy locations in the United States as of December 25, 2024. The state and territory with the most number of The Medicine Shoppe Pharmacy locations in the US is Pennsylvania, with 37 locations, which is about 12% of all The Medicine Shoppe Pharmacy locations in the US.
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Note: To ensure accurate industry categorization, we utilize NAICS codes, which classify businesses by their main economic activity. As a result, companies may appear in different industry location reports based on their primary NAICS classification. For instance, Walmart is classified as a department store under NAICS.
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